The Apothecary Diaries has just delivered its Season 2 finale, and with it came an exciting announcement that fans had been eagerly hoping for. A brand new sequel anime is officially in production, marking the next chapter in the journey of Maomao, the clever and curious apothecary who continues to captivate audiences with her intelligence and rebellious charm. The announcement arrived right after the broadcast of Episode 24 of Season 2, which is also the 48th episode overall in the series. The episode, titled “The Beginning,” closed out the second season with emotional weight and narrative momentum, setting the perfect stage for what comes next.
While many fans expected a traditional third season, the new installment is specifically referred to as a sequel anime rather than a continuation under the typical seasonal format. This choice has sparked intrigue, suggesting that the upcoming project may come with a shift in tone, format, or even storytelling structure. Whether it will be a film, a new series arc, or a different kind of production entirely has yet to be clarified, but anticipation is already running high across the community.
The anime has been streaming on Crunchyroll for global audiences, while Netflix has carried it in select Asian territories. Its popularity has only grown over time, bolstered by consistently strong storytelling, detailed historical setting, and a compelling protagonist who never fails to leave an impression. Maomao’s unique blend of scientific logic, dry humor, and social defiance has made her one of the most distinctive female leads in recent anime. Her dynamic with Jinshi, the mysterious and elegant palace official, continues to evolve in ways that add emotional depth and romantic tension without overshadowing the main story.
The series originates from the light novel written by Natsu Hyuga and illustrated by Toko Shino. It has since expanded into two separate manga adaptations. One is written by Itsuki Nanao and illustrated by Nekokurage, while the other is created by Minoji Kurata. J Novel Club currently publishes the light novels in English, and Square Enix handles the manga editions, helping the franchise build a global audience.
At its core, The Apothecary Diaries is a rich historical mystery drama set within the inner walls of the emperor’s palace. When Maomao is sold into palace servitude, she finds herself drawn into court politics, health scandals, and even criminal investigations all using her deep pharmaceutical knowledge and unshakeable curiosity. Far from being a passive servant, she pushes boundaries, questions power, and uncovers hidden truths. This makes the announcement of the sequel especially exciting, as the story’s world still holds many secrets left to unravel.
The new visual and trailer released alongside the announcement tease Maomao’s continued role in the imperial court and suggest even deeper entanglements with Jinshi. With so many character arcs still unfolding and mysteries left unsolved, the sequel offers a chance to further explore the emotional complexities and societal undercurrents that have become central to the show’s appeal.
As fans wait for more details regarding the format and release date of the sequel, one thing is clear. The Apothecary Diaries has firmly secured its place among the most beloved anime of recent years, and its story is far from finished.
For the latest updates on The Apothecary Diaries and all your favorite anime news, follow Anime Insider on Instagram and Facebook.